Synthesis of Pyridazine-Based α-Helix Mimetics.
نویسندگان
چکیده
A versatile synthesis of pyridazine-based small molecule α-helix mimetics (A) is presented. Modular C-C, C-N, and C-O bond-forming reactions allow for the inclusion of a variety of aliphatic, basic, aromatic, and heteroaromatic side chain moieties. This robust synthesis is suitable for the preparation of small pyridazine-based libraries.
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عنوان ژورنال:
- ACS combinatorial science
دوره 18 10 شماره
صفحات -
تاریخ انتشار 2016